Prevent & Reverse Heart Disease
                    By: Caldwell B. Esselstyn, Jr., M.D.  
                                        Book Review By: Clarence Bass
                Muscle & Fitness Columnist

If you were told that a strict plant-based diet would prevent and even reverse
heart disease, would you adopt the diet?  

What if you had advanced heart disease and were facing open-heart surgery
or balloon angiography?  

Based on clinical experience, conventional medicine says you are not likely to
radically change your diet in either case.  

Caldwell B. Esselstyn, Jr., MD, formerly a surgeon, researcher and clinician at
Cleveland Clinic, says the odds are high that you would choose the diet—if
your doctor took the time to fully and completely explain the benefits.  

Both are probably correct.  Most people are not willing to change.  
Nevertheless, we should be given full information and every opportunity to
help ourselves.  

You should know about the success Dr. Esselstyn has had with diet and, if
necessary, minimal use of cholesterol lowering drugs.  

His diet rules are simple—and strict:  All vegetables, fruit, whole grains, beans
and lentils are allowed; but no meat, chicken, fish, eggs, refined grains, dairy
products (even skim milk), oil, nuts or avocados.  

In short, eliminate all fats except those found in plant-based foods; no animal
foods or concentrated fats (oil, nuts).  

His aim is to avoid any food known to cause or promote vascular disease.  If
you are free of heart disease, walnuts in moderation are permitted.  

Esselstyn acknowledges that the omega-3 fatty acids found in fish are
essential to artery health and other bodily functions, but prefers to use plant
sources, such as flaxseed.  

Although his diet sounds—and is—Spartan, Dr. Esselstyn’s meal suggestions
are more satisfying—rabbit food it’s not—than you might think.  

And, the choices begin to have more appeal when you learn the results of his
20-year nutritional study.  
Dr. Esselstyn says:

“My approach is not another stop-gap solution, it prevents heart disease from
occurring in those who don’t yet have the disease, and it heals the body and
reverses the disease when symptoms are present.”

            Study Results
The patients in the study had advanced heart disease.  They were literally at
death’s door.  Despite aggressive treatment—think bypass and stents—most
were told they had less than a year to live.  

They were referred to Dr. Esselstyn as a last resort.  He sat down with each
patient for up to an hour (as long as necessary) and explained the benefits of
plant-based nutrition.  

He also explained that surgical repairs do not stop the progression of the
underlying disease; that lifestyle change is the only way to stop or reverse
their disease.  He gave them reason for hope.  

Within months on Dr. Esselstyn’s program, their cholesterol levels, angina
symptoms, and blood flow improved dramatically.  Twenty years later, most of
them are still alive.  Sounds almost too good to be true, doesn’t it?  Here are
the details.  

Six patients opted out; they did not grasp what Dr. Esselstyn was trying to do
and were not willing to follow the diet.  

Seventeen patients signed on to the program.  Each was put on a plant-based
diet and given a prescription for a cholesterol-lowering drug.  

Every two weeks for five years—this is very important—Esselstyn contacted
each patient to go over what they were eating, cholesterol readings, problems,
etc., and make necessary changes in their nutrition or medication.  

This level of contact is, of course, almost unprecedented.  It really paid off.  It
was the key to keeping them on the diet.  The continuous encouragement and
guidance—and the symptom relief they were experiencing.  

Dr. Esselstyn goes over the history of each patient in his book, but here is an
overview of what happened.  

One patient, who was accepted into the program after sustaining massive
heart damage (function reduced to 20%), died after surviving five years on the

Despite showing improved blood supply and decrease in angina, he died of
cardiac arrhythmia.  
“Postmortem study showed no new blockages or heart
Dr. Esselstyn relates.  The other patients improved and survived.  

As a group, the patients began the study with average total blood cholesterol
of 246; desirable is 200 or less.  

By adhering to the diet and using cholesterol-lowering drugs, their average
cholesterol dropped to 137; less than 150 is ideal and considered protective.  

Their cholesterol went from
“high risk” to “safe” on the program:  “Below 150
is the total cholesterol level seen in cultures where heart disease is essentially

Dr. Esselstyn tells us.  Every participant achieved a total cholesterol level
below 150.  

Almost half of the participants showed a widening of their coronary arteries—
an actual reversal of their disease.  This is not opinion; it is documented fact.  

Angiogram X-ray pictures were taken at the beginning of the program, and
after five years:

“At the five-year mark, seven of the eighteen participants were unable to have a
follow-up angiogram”
 Dr. Esselstyn writes: “The results I report here are for
the eleven participants who did have follow-up angiograms after five years.  
The analyses were stunning.  In sustaining cholesterol readings below 150,
these patients eliminated any clinical progression of their disease.  Every single
one arrested progression of the heart disease, and eight participants actually
selectively reversed it.”  

A color insert in the book shows the angiogram pictures.  You can see the
improved blood flow, in some cases after only 3 weeks.  The results are indeed

Finally, and most importantly, for all participants, symptoms improved.  
of the patients had come to the study with angina—pain in the heart muscle
caused by inadequate blood supply”

Dr. Esselstyn reports:

“It was completely eliminated in two and much improved in the remaining
seven, including the patient who died.  Exercise capacity improved.  Sexual
activity was enhanced.”  

                                                   The Explanation
Here’s how Dr. Esselstyn describes what happened to the people in the study:

“The blood supply through their coronary arteries to their heart muscles has
improved.  In the majority of patients, the arteries themselves are measurably

Exploring the causative factors, Dr. Esselstyn continues:

“Profound reduction of cholesterol has increased the capacity of the
endothelium, the arteries’ inner lining, to produce nitric oxide, which in turn
dilates [expands] the arteries themselves—even diseased arteries.”  

On the role of the diet, he adds:

“The patients’ plant-based diet, eliminating the ingestion of foods that injure
vascular tissues, has restored strength and integrity to the endothelium as a

Importantly, “Any plaques in these patients were protectively capped and could
not rupture or initiate the cascade of clotting that defines a heart attack.”  

“These patients are now heart-attack-proof”
 Esselstyn states emphatically.  


I’m impressed—and encouraged.  My diet is largely plant-based, but not as
strict as Dr. Esselstyn would like.  

“I stress the need for total commitment” says the doctor.  “My first request is
that patients and their families eliminate from their vocabulary, from their
thinking, from their basic belief systems, the phrase ‘This little bit can’t hurt.’”
He adds,
“That just a little bit of forbidden food—fats, dairy products, oils,
animal proteins—can hurt, and will.”  

I wouldn’t pass muster, because I use a small amount of canola oil, measured
amounts of nut butter, several cups of skim milk and non-fat yogurt, and
frequently have modest portions of fish or (less often) chicken with my
evening meal.  

I also eat two to four eggs a week. This seems to be working well for me,
based on the results of my latest blood test.  

My total cholesterol is 158, about 5% over Dr. Esselstyn’s
“safe” number.  I
believe that puts me in a pretty good place, because my HDL
cholesterol, at 62, is almost twice the 36-average level for the participants in Dr.
Esselstyn’s study.  

My total cholesterol-HDL ratio is substantially better than the study
participants, 2.55 to 3.8; <4.5 is considered acceptable.  My LDL
cholesterol, at 82, is the same as the average for the participants, but my HDL-
LDL ratio is far better, 1.32 compared to 2.28.  

I believe my high HDL is due to daily exercise (weights, aerobics or walking),
something that Esselstyn encourages, but does not require.  

Carol and I are making some changes, nevertheless.  For one thing, we’re
going to include Dr. Esselstyn’s
“thick soup” suggestions several times a
week in our evening meal.  We’ve already tried the
“Sweet Potato and Lentil
Soup with Shiitake Mushroom.”
 It’s delicious and very satisfying.  

We’re also looking for other places to use Esselstyn’s recipes, and reduce
unhealthy fat.  (Some fat in the diet is desirable.  Adding a tablespoon of oil—
olive and then flaxseed—reduced my triglycerides by half.  

Could your diet be improved?  Before you decide, I encourage you to read Dr.
Esselstyn’s inspiring book
Prevent and Reverse Heart Disease.  

By: Clarence Bass  

Book Review:
Prevent & Reverse Heart Disease  

Dr. Esselstyn’s website: